Research

Ongoing research projects

2022 Italian Ministry of University and Research - Progetto di Ricerca di Interesse Nazionale (PRIN) “Biochemical mechanisms and cellular consequences of mitochondrial cation flux: from bioenergetics to metabolic rewiring" (P.I. L. Palmieri)

2021 Italian Association for Cancer Research (AIRC). MOnARCHY - Dissecting the Metabolic signature of high-grade serous OvARian cancer: a challenge to overcome CHemotherapY. (PI: A.M. Porcelli)

2020 Italian Association for Cancer Research (AIRC). Assessing the Efficacy of Mitochondrial Complex I Targeting in Combined Therapies for Ovarian Cancer - AMICO (PI G. Gasparre)

 

Ended research projects

2018 – 2020 University of Bologna, ALMAIDEA Linea d’Intervento Giovani. INTACt: Induzione della pseudoNormossia come Terapia Adiuvante per il Cancro. (P.I. L. Iommarini)

2017 – 2020 EU H2020 Marie Curie ITN grant 722605  TRANSMIT: Translational significance of mitochondria in tumors. (PI A. M. Porcelli)

2016 – 2019 Italian Health Ministry grant GR-2013-02356666 DISCOTRIP: Disrupting mitochondrial complex I to trigger pseudonormoxia: an anticancer strategy. (PI G. Gasparre)

2016 – 2019 Worldwide Cancer Research grant DhoMoS: Understanding the determinants of the homoplasmic shift of mitochondrial DNA mutations in families with recurrent oncocytomas. (PI G. Gasparre)

2016 – 2018 Italian Association for Cancer Research (AIRC). TOUChMe: Taxane Resistance in Ovarian Cancer: Understanding the Contribution of Mitochondrial Metabolism Defects. (PI A. M. Porcelli)

2013 - 2017 Marie Curie Initial Training Networks (FP7-PEOPLE-2012-ITN) 2013-2017 “MEET-Mitochondrial European Educational Training”. (PI G. Gasparre)

2013 – 2015 Italian Association for Cancer Research (AIRC). JANEUTICS: From the oncojanus function of mitochondrial genes to anti-cancer therapeutic strategies. (PI G. Gasparre)

2012 – 2013 Fondazione Umberto Veronesi Grant. DISCO TRIP - Disrupting complex I to trigger pseudonormoxia. (PI G. Gasparre)

2012 – 2014 United Mitochondrial Diseases Foundation Grant. Estrogen mediated regulation of mitochondrial biogenesis and functions: possible therapeutic implications for Leber’s hereditary optic neuropathy. (PI C. Giordano)

2010 – 2013 Futuro in Ricerca (FIR) grant J31J10000040001. TRANSMIT: Translational significance of mitochondrial mutations in tumors. (PI G. Gasparre) 

2009 – 2011 Italian Association for Cancer Research (AIRC) grant IG8810. TRANSMIT: Translational significance of mitochondrial mutations in tumors. (PI G. Romeo)

2008 - 2010 - Italian Ministry of University and Research - Progetto di Ricerca di Interesse Nazionale (PRIN) “Role of mitochondria in the regulation of apoptosis and autophagy: molecular mechanisms and effects of pathogenic mutations”. (P.I. P. Pinton)

2007 – 2010 Telethon grant GGP06233B. Pathogenic mechanisms for degeneration of retinal ganglion cells in mitochondrial optic neuropathies.  (PI V. Carelli)