Former PhD student
Supervisor: Prof. Andrea Bedini
Co-supervisor: Monica Baiula
PhD Thesis: Cellular signalling and molecular pathway analysis in specific neuronal cell models - QSPainRelief EU H2020 Project
Project Description: The aim of the PhD research project is to produce quantitative data from in-vitro molecular pathway analysis in specific cell models (i.e. primary cultures from rat and mouse, SH-SY5Y human neuroblastoma cells, and sex-differentiated mouse organotypic brain slice cultures) in order to contribute to the QSPainRelief platform implementation. The overarching goal of this 5-year-long EU-funded research project is to identify alternative combinational treatment paradigms, with improved analgesia (pain relief) and reduced adverse effects via a mechanism-based QSP approach, using algorithms and advanced in silico technologies.