Investigating neurodegeneration in human midbrain organoids

  • What it is

    Mobility experience with a research focus

  • Who it’s for

    PhD sandwich; Post Doc

Department

Veneto Institute of Molecula Medicine (VIMM)/Padua Neuorscience Center (PNC)

Main research activities/topics/projects

We are interested in the study of neuronal and glial dysfunction due to specific variants of genes (PARK2, GBA, etc…) involved in the pathogenesis of Parkinson’s disease. 2D and 3D (organoid) models derived from human induced pluripotent stem cells (iPSCs) will be analyzed by biophysical techniques, such as electrophysiology (patch-clamp, MEA) and optical fluorescence microscopy of Ca2+ sensors.

Working language

English

Special entry requirements

Experience in electrophysiology and/or optical fluorescence microscopy is required. Data analysis skills with Matlab or ImageJ are also welcome.

Duration in months (min-max)

PhD sandwich: 10-15
Post Doc: 10-15

Highlights

Contacts

Main scientific contact person

Mario Bortolozzi
Associate Professor of Biological Physics at the Department of Physics and Astronomy "G.Galilei", University of Padua, via Marzolo 8, 35131, Padova.
Group Leader at the Venetian Institute of Molecular Medicine (VIMM), via G. Orus 2, 35129 Padova, Italy

+390497923237/250

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