Mobility experience with a research focus
PhD sandwich; Post Doc
Department of Biology
Mitochondrial versatility in metabolism, signalling and cell death is mirrored by their dynamic morphology, ultrastructure and juxtaposition to the endoplasmic reticulum, all controlled by a set of “mitochondria-shaping proteins”. We are interested in understanding the mitochondrial form-function relationship in health and disease. We use an integrated approach of genetics, advanced imaging, biochemistry, physiology and electron tomography to unravel the role of mitochondrial dynamics in signalling and in complex cellular responses. Interested students/postdocs will join projects aimed at addressing the molecular mechanisms of mitochondrial structure regulation, the role of Opa1-regulated mitochondrial ultrastructure in tissue damage, the role of mitochondrial shape and of autophagy in heart diseases, the role of mitochondrial remodeling in metabolism and cancer, or the molecular mechanisms and physiological consequences of ER-mitochondria tethering.
The group is large and multinational and the only working language is English.
Lab experience
PhD sandwich: 8-12
Post Doc: 8-12