Discovering subpopulations using innovative curve clustering

Novel Curve Clustering

  • Date: 13 JUNE 2023  from 17:30 to 19:00

  • Event location: Institute of Advanced Studies - Sala Rossa, Palazzo Marchesini, Via Marsala, 26 - Bologna - In presence and online event

  • Type: Lectures

Knee osteoarthritis (OA) is a common, incurable, painful and debilitating disease that is likely influenced, in part, by biomechanical factors. For example, ground reaction force (GRF) and knee joint kinematics likely affect knee OA onset time and progression rate. Knee OA often occurs after anterior cruciate ligament and surgical reconstruction (ACLR). One third to one half of ACLR patients suffer from knee OA in the first decade after surgery. We detail a new statistical technique that is able to discover subgroups of patients that negotiate particular movement tasks in unique ways. This is done by group individuals based on similarity of measured output (i.e., force) but also using similarity of pattern on how movement was negotiated. Unearthing these types of subgroups will provide insights regarding which biomechanical factors predispose ACLR patients to knee OA. Although knee OA is the context we use to illustrate the new statistical technique, our method will be useful to any scientific field that produces data that are curves.

Speaker

ISA Visiting Fellow - Garritt Page

Brigham Young University, U.S.A.

Visit Prof. Page's web page

PhD students and researchers who are interested may request an attendance certificate.